Publications by authors named "D Markov"

Article Synopsis
  • Respiration in eukaryotes relies on mitochondrial protein synthesis, which is guided by organelle-specific ribosomes that translate mitochondrial mRNAs, although many details of this process remain unclear.
  • Researchers mapped the 3' ends of mitochondrial mRNAs in different yeast species and identified sequence elements called 3'-end RNA processing elements (3'-RPEs), essential for processing mitochondrial RNA.
  • The study highlights the role of the Rmd9 protein in this processing, showing its interaction with 3'-RPEs across various yeast species, and uncovers a unique translation mechanism involving removed stop codons in certain mRNAs.
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The specificity of the medical profession, which involves constant communication with sufferers and their loved ones; the need to quickly master rapidly developing medical technologies and the digital environment; organizational and economic changes in the healthcare system that are increasingly intensifying the work of medical workers create a risk of expanding the scope and aggravation of the problem of professional burnout. The article presents an analysis of approaches to identifying signs and classifying the stages of professional burnout among medical workers, as well as methods for preventing and relieving this syndrome in domestic and foreign practice. In addition, the results of two mass surveys of medical specialists employed in the Moscow healthcare system, conducted at five-year intervals, are presented.

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The COVID-19 coronavirus pandemic significantly impacted processes of medical care support and medical personnel and managers. The article presents analysis of results of three-year (2019-2022) studying level of loyalty of legal representatives of patients of one of Moscow children polyclinics. The study covered both legal representatives of patients (more than 190,000 assessments collected over entire observation period) and randomly selected district pediatricians (n=31).

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Soft tissue sarcomas arising from the chest wall are an extremely rare entity. They are classified as mesenchymal tumors of varying aggression. It is this unpredictable behavior that makes them an unexpected hurdle even for experienced surgeons.

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Differential access to pathological sellar processes and adjacent regions is determined by the anatomic structures identified through diagnostic imaging. Both direct endonasal access (microscopic or endoscopic) and sublabial access utilize the sphenoid sinus (SS) as the primary surgical pathway. Critical factors include the pneumatization of the sinus, its intermediate septa, and the presence of a double wall, consisting of a connective tissue membrane along the dorsal wall of the SS.

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