Publications by authors named "D Marakushyn"
Expression features of T-lymphocytes, B-lymphocytes and macrophages in the post-traumatic regenerate of the mandible rats under conditions of filling a bone defect with hydroxyapatite-containing osteotropic material and thymalin injecting the surrounding soft tissues.
Pol Merkur Lekarski
April 2024
Article Synopsis
- The study aimed to explore how T-lymphocytes, B-lymphocytes, and macrophages express in the mandible of rats after a simulated bone injury, particularly focusing on the effects of using hydroxyapatite-containing material and thymalin injections.
- Conducted on 48 mature rats divided into four groups, the experiment involved creating bone defects and employing different treatments including bone grafts and thymalin to assess their impact.
- Results showed that thymalin injections significantly enhanced the local immune response, increasing both T-lymphocyte and B-lymphocyte counts at various points throughout the 28-day observation period.
The study was conducted as a part of research work "Biochemical mechanisms of the development of dismetabolic processes under the influence of chemical environmental factors". The purpose of the present work was to study the effects produced by sodium salts of carboxymethylates of oxyethylated isononylphenols on the state of the microsomal monooxygenase system of hepatocyte detoxification and on the conjugation reaction in conditions of a subacute experiment and to reveal a potential danger for homoitherms and human beings. The object of the study were the white rats of WAG population.
View Article and Find Full Text PDFAim To investigate the lipid membranes of rat enterocytes in chronic carrageenan-induced gastroenterocolitis accompanied by the activation of apoptotic processes. Methods Steady-state fluorescence spectroscopy: a study by fluorescent probes - by ortho-hydroxy derivatives of 2,5-diaryl-1,3- oxazole. Activity of apoptosis signal-regulating kinase 1 and poly (ADP-ribose) polymerase in small intestinal homogenates, blood serum levels of matrix metalloproteinase-2 and caspase-3 and the level of DNA fragmentation in small intestinal homogenates were determined.
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