Publications by authors named "D Malicki"
Article Synopsis
- - A delayed hemolytic transfusion reaction (DHTR) can occur in sickle cell disease (SCD) patients after receiving blood transfusions, leading to serious anemia weeks later due to immune responses to foreign red blood cell antigens.
- - The case study describes a pediatric SCD patient who experienced DHTR after her second transfusion, emphasizing the importance of extending RBC antigen profiling through molecular genotyping instead of just serology.
- - Molecular genotyping offers better accuracy in matching blood types, which can help prevent complications during transfusions and improve management by quickly identifying rare donors when needed.
Background: Trauma remains the leading cause of pediatric mortality in the United States. Although use of massive transfusion protocols (MTPs) in this population is widespread, optimal pediatric resuscitation is not well established. We sought to assess contemporary pediatric MTP practice in the United States.
View Article and Find Full Text PDFStandardizing visual display of gastrointestinal pathology results for improved clinical interpretation.
J Pediatr Gastroenterol Nutr
September 2024
Objectives: Pathology is an essential component of disease diagnosis and management in pediatric gastroenterology. Pathology reports have not been standardized in some areas of pediatric gastrointestinal pathology and pathology reporting varies. Development of electronic medical record (EMR) pathology synoptic report templates (PSRT) enables pathology data collection in a specific format and can help standardize pathology reporting.
View Article and Find Full Text PDFImportance: Young children are ingesting illicit drugs at increased rates, but it is unknown what the associated child protection system (CPS) responses are when a child tests positive.
Objective: To document the child protection system involvement and the characteristics of children who test positive for illicit substances.
Design, Setting, And Participants: This retrospective cross-sectional study linked medical discharge and child protection system administrative data.
Pathogenic variants in the DES gene clinically manifest as progressive skeletal muscle weakness, cardiomyopathy with associated severe arrhythmias, and respiratory insufficiency, and are collectively known as desminopathies. While most DES pathogenic variants act via a dominant mechanism, recessively acting variants have also been reported. Currently, there are no effective therapeutic interventions for desminopathies of any type.
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