Publications by authors named "D Maki"

Objectives: In recent years, there has been a notable increase in syphilis cases in Japan and Western countries. Syphilis, a classic sexually transmitted disease caused by treponemas, presents diagnostic challenges due to its diverse clinical manifestations. This study explores the diagnosis of syphilis in patients treated at our hospital.

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Background: Recurrent or metastatic squamous cell carcinoma of the head and neck (R/MHNSCC) is a challenging malignancy with a poor prognosis and limited treatment options. Nivolumab, an immune checkpoint inhibitor (ICI) targeting the programmed cell death/programmed cell death ligand 1 (PD-1/PD-L1) pathway, has emerged as a promising therapy for these patients. However, identifying biomarkers predictive of response to nivolumab remains critical for optimizing treatment strategies.

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Article Synopsis
  • Rising recidivism is threatening the positive effects of vaccinations in the US, largely due to vaccine hesitancy and other complex factors.
  • The future looks promising thanks to advancements in vaccine technology and the commitment of healthcare professionals and public health systems, which are crucial for eliminating infectious diseases.
  • To effectively increase vaccination rates, healthcare providers must focus on rapid detection, isolation, and a comprehensive response strategy, including antiviral medications and social distancing measures.
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  • The study examines the effectiveness of a new treatment in managing a specific health condition, showing promising results in patient outcomes.
  • Researchers conducted a clinical trial involving diverse participants, ensuring the findings are applicable to a broader population.
  • The results suggest that the treatment could be a viable option for clinicians, potentially changing current practices in managing the condition.
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Article Synopsis
  • * The treatment involved antibiotics, extraction of a decayed tooth, and drainage of the sinuses and abscess, with a positive prognosis after 1 year and 5 months without complications.
  • * The case highlighted a potential link between dental infections and serious conditions like brain abscesses, emphasizing the need for timely dental care in children.
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