Publications by authors named "D Major"
Background: Chronic obstructive pulmonary disease (COPD) is a progressive, inflammatory airway disorder characterized by a gradual decline in lung function and increased oxidative stress. Both oxidative stress and inflammation are central to its pathophysiology, with trace elements such as zinc, copper, iron, manganese, magnesium, selenium, and calcium playing key roles in various cellular processes.
Objective: This article reviews the role of trace elements in COPD, focusing on their involvement in disease pathogenesis and their therapeutic potential.
Article Synopsis
- Obesity is a major risk factor for dementia, with a study analyzing its global impact and examining how national obesity strategies influence dementia rates, especially considering differences between genders.
- The research found that for every 1% increase in obesity prevalence, dementia mortality rises by 0.36% in males and 0.12% in females, indicating that men are more affected by obesity-related dementia.
- Implementing national obesity management strategies and promoting healthier diets can significantly reduce dementia prevalence and mortality, particularly benefiting women, suggesting the importance of public health initiatives to tackle obesity.
Introduction: The COVID-19 pandemic affected adolescents' mental health diversely.
Methods: Our objective was to examine the one-year change in well-being (WHO-5 well-being index) and self-esteem (Rosenberg self-esteem scale) among secondary school students affected by school lockdown (lockdown group) compared to control students unaffected by the pandemic (pre-pandemic group), utilizing data from a longitudinal survey study conducted in Hungary. We used linear mixed models stratified by sex and adjusted for family structure and family communication.
Since its inception nearly a half century ago, CHARMM has been playing a central role in computational biochemistry and biophysics. Commensurate with the developments in experimental research and advances in computer hardware, the range of methods and applicability of CHARMM have also grown. This review summarizes major developments that occurred after 2009 when the last review of CHARMM was published.
View Article and Find Full Text PDFAims: To estimate prevalence of diagnosed (dDM) and undiagnosed diabetes (uDM) in Hungary and investigate determinants of uDM.
Methods: Data was obtained from the nationally representative H-UNCOVER study. As laboratory measurements were available for 11/19 Hungarian counties, n = 5,974/17,787 people were eligible.