Publications by authors named "D Mahato"

Foodomics is an interdisciplinary field that integrates various omics technologies to explore the complex relationship between food and human health in depth. This approach offers valuable insights into the biochemical, molecular, and cellular composition of food by employing advanced omics techniques. Its applications span the food industry and human health, including efforts to combat malnutrition, provide dietary recommendations, and ensure food safety.

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Camptothecin (CPT), an alkaloid isolated from the Camptotheca tree, has demonstrated significant anticancer properties in a range of malignancies. However, its therapeutic efficacy is limited by its hydrophobicity, poor bioavailability, and systemic toxicity. Derivatives, analogues, and nanoformulations of CPT have been synthesized to overcome these limitations.

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This report presents a 14-year-old male with seizures and facial port-wine stains, who upon further evaluation was found to have SWS. Early diagnosis and consistent treatment of Sturge-Weber syndrome in children are essential to prevent seizures and improve quality of life. Anti-seizure medications play a crucial role in preventing and controlling seizures.

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Article Synopsis
  • This study examines the effectiveness of rosemary extract (RE) in enhancing the stability of structured lipids made from perilla seed oil and palmolein under high-temperature storage.
  • The results showed that oil samples with 1500 ppm of RE had significantly better oxidative stability and improved quality parameters compared to those without any antioxidants, achieving reductions in several harmful indicators like free fatty acids and TOTOX value.
  • The study concluded that RE acts similarly to the synthetic antioxidant BHT, effectively inhibiting oxidation of polyunsaturated fatty acids and preserving beneficial compounds during storage.
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In the modern era, nanomedicine has developed novel drug-delivery strategies to improve chemotherapy. Nanotechnological-based treatment approaches for cancer through targeted tumour drug delivery and stimulus-responsive tumour microenvironment have gained tremendous success in oncology. The application of building block materials of these nanomedicines plays a vital role in cancer remediation.

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