Herein, we disclose the hitherto unknown cross-conjugated vinylogous annulation of π-CF-allyl Pd complexes with 4-methyl-3-trifluoroacetyl-quinolones to access phenanthridones. The CF group in the Pd-π-allyl complex is key for exclusive γ-regioselectivity and further annulation. The solvent switch orchestrates the dihydro-phenanthridones (CHCN) and hydroxy-phenanthridones (DMF) in good yields, and also showed excellent optoelectronic properties.
View Article and Find Full Text PDFEndoscopic ultrasound (EUS)-guided biliary drainage (EUS-BD) includes EUS-guided hepaticogastrostomy (EUS-HGS), EUS-guided choledochoduodenostomy (EUS-CDS), EUS-guided gallbladder drainage (EUS-GBD), EUS-guided antegrade stenting (EUS-AG) and EUS-guided rendezvous (EUS-RV). While EUS-HGS, EUS-CDS and EUS-GBD are transluminal drainage procedures, EUS-AG is a traspapillary drainage procedure and EUS-RV is a procedure intended to facilitate endoscopic retrograde cholangio pancreatography (ERCP) in instances of failed cannulation. These procedures were initially developed as options for endoscopic salvage of failed ERCP, but have evolved to become first-line interventions also for select indications over time as the technique and expertise improved.
View Article and Find Full Text PDFJ Hazard Mater
October 2024
This study presents a distinctive solid-state naked-eye colorimetric sensing approach by encapsulating a chromoionophoric probe onto a hybrid macro-/meso-pore polymer scaffold for fast and selective sensing of ultra-trace Hg(II). The customized structural/surface properties of the poly(VPy-co-TM) monolith are attained by specific proportions of 2-vinylpyridine (VPy), trimethylolpropane trimethacrylate (TM), and pore-tuning solvents. The interconnected porous network of poly(VPy-co-TM), inherent superior surface area and porosity, is captivating for the homogeneous/voluminous incorporation of probe molecules, i.
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