Biomolecular docking interactions, cytotoxicity and antioxidant property evaluations with novel Mn(II), Ni(II), Cd(II) and Pb(II) Schiff base ligand complexes: Synthesis and characterization.

The development of Schiff base-centered medical chemistry in conjunction with the use of less-expensive transition metals with high pharmacological activity has currently triggered enormous interest in the development of novel Schiff base ligands. In this context, four different metal complexes comprising Mn(II), Ni(II), Cd(II) and Pb(II) (labeled as complexes 1-4) were synthesized using a novel tetra-dentate ligand (L) obtained by condensation of 3,5-dichlorosalicylaldehyde and trans-1,2-diaminocyclohexane, as demonstrated herein. The physico-chemical properties of the complexes were evaluated through UV-Vis, FT-IR, NMR, TGA, powder XRD and ESI-MS analyses.

Fabrication of poly (methyl methacrylate)/Ce/Cu substituted apatite/Egg white (Ovalbumin) biocomposite owning adjustable properties: Towards bone tissue rejuvenation.

A new biocomposite including Poly (methyl methacrylate)/Ce-Cu substituted apatite/Egg white (Ovalbumin) (PMMA/MHAP/EW) has been effectively manufactured via lyophilization technique. The reason to plan such biocomposite is to investigate for a perfect simple which may bio-imitate the constitution of natural bone for hard tissue designing regarding appropriate biodegradability, biocompatibility, and bactericidal properties. The FTIR and XRD spectra of prepared biocomposite showed the considerable intermolecular interface between the different constituents of the biocomposites.