Current anthelmintic and antibiotic use in UK organic farming systems.

Introduction: The use of anthelmintic and antibiotic medicines is imperative to prevent the suffering of diseased stock in organic farming. However, their use must be minimised to comply with low input ideals and prevent the spread of resistance. Reducing such inputs first requires determining their current use, but information is lacking.

Relationships between the developmental potential of human in-vitro fertilization embryos and features describing the embryo, oocyte and follicle.

This paper investigates the relationship of features of in-vitro fertilization (IVF) embryos and the associated oocyte and follicle to the outcome of transfer. It differs from previous studies in including a range of features (n = 53) and in using class probability tree analysis. This is a non-parametric multivariate method which expresses relationships as simple rules of features characterizing the 'take home baby' and 'no take home baby' (negative pregnancy test) classes of embryo batches.

Effects of zatebradine (ULFS 49 CL), a sinus node inhibitor, on heart rate and exercise duration in chronic stable angina pectoris. Zatebradine Investigators.

Zatebridine selectively reduces resting and exercise heart rate without any other myocardial effects. In this study, despite significant reductions in resting and exercise heart rate, there were no clinically significant effects on myocardial ischemia, suggesting that the anti-ischemic effect of heart rate reduction should be reevaluated.

The safety, tolerability, and pharmacokinetics of fosphenytoin after intramuscular and intravenous administration in neurosurgery patients.

Study Objective: To evaluate the safety, tolerability, and pharmacokinetic profile of fosphenytoin, a water-soluble phenytoin prodrug, after intramuscular and intravenous administration.

Design: Open-label study of intramuscular administration, and double-blind, randomized study of intravenous administration.

Setting: Six and ten hospitals throughout the United States for the intramuscular and intravenous multicenter studies, respectively.

The Investigators' Meeting: Obtaining Maximum Results.

This survey was undertaken to ascertain what clinical investigators liked and disliked about the meetings that precede the initiation of clinical trials and to determine if there are any differences in opinion between those investigators engaged in private practice and those affiliated with academic institutions. A 16-item multiple choice survey was mailed to 565 clinical investigators. Sixty-three percent of those polled returned the survey.