Publications by authors named "D M Thompson"
Article Synopsis
- The study investigates CP symmetry violation in the decay of D^{+} particles into K^{-}K^{+}π^{+} using data from proton-proton collisions at a high energy of 13 TeV.
- A unique model-independent method was employed to analyze the phase-space distributions of D^{+} and D^{-} particles, correcting for any instrumental biases using D_{s}^{+} decays.
- The findings indicate no significant evidence of CP violation, with a p value of 8.1%, and measure specific CP asymmetry observables, marking this study as the most sensitive search of its kind in multibody decays.
The remediation of antimicrobial resistance (AMR) is a fundamental challenge for global healthcare. Intrinsically disordered proteins (IDPs) are recognized drug targets for neurodegeneration and cancer but have not been considered to date for AMR. Here, a novel link between structural disorder and AMR is identified by mapping predicted disorder profiles onto existing transcriptomic data for resistant and susceptible isolates.
View Article and Find Full Text PDFInhalation exposure to respirable crystalline silica (RCS) during the fabrication of engineered stone-based kitchen countertops has been on the rise in recent years and has become a significant occupational health problem in the United States and globally. Little is known about the presence of nanocrystalline silica (NCS), i.e.
View Article and Find Full Text PDFBackground: Approximately 80% of nasal masses in dogs and 91% of nasal masses in cats are reported to be malignant, but the currently reported diagnostic rate of neoplasia is 54% using blind or rhinoscopic biopsy techniques.
Hypothesis/objectives: Describe the technique of computed tomography (CT)-guided Tru-Cut (Tru-Cut biopsy needle, Merit Medical Systems, Utah, USA) nasal biopsies in cats and dogs to determine the diagnostic rate of neoplasia on the first round of sampling and to evaluate the safety of the technique.
Animals: Thirty client-owned animals, 16 dogs and 14 cats, that had CT-guided nasal biopsies performed to investigate nasal masses.
Lipocalin-2 (LCN2) is an acute-phase secretory molecule significantly upregulated in various neuroinflammatory and demyelinating conditions. Krabbe disease (KD) is a neurodegenerative lysosomal disorder caused by a galactosylceramidase (GALC) deficiency, accumulating cytotoxic psychosine in nervous systems, and subsequent neuroinflammation. Here, we show that LCN2 is highly overexpressed in GALC-deficient astrocytes.
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