Publications by authors named "D M Samarin"

The paper describes the case of a rare hereditary disease--Incontinentia Pigmenti syndrome incontinence of pigment in newborn.

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The main aim of the study was determination of leukocyte indexes and identify their possible use to diagnose obstructive bronchitis in children.

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On the basis of analysis of experience of eliminate the consequences of derailing train accidents given the classification of emergency situations, set the features predict the expected health loss under the explosion of various damaging factors. The recommendations concerning the planning of medical consequences control after railway accidents with hazardous cargo are given.

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The history of researches of a problem of cancer has cleared a number of key cellular-molecular-genetic mechanisms of carcinogenesis, however process of carcinogenesis, is still out of control and a world forecast is unfavorable despite the advanced pathogenetically focused medication and excellent results of cancer treatment in vivo. Numerous researches have shown that chronic psycho-emotional stress by means of stressful hormones and endogenous mutagens (reactive oxygen and nitrogen species) are capable to damage cells DNA and to compromise immune system. Actually, chronic psycho-emotional stress is capable to activate the key mechanisms of carcinogenesis.

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Two-staged technology for obtaining polyclonal T cell vaccine intended for the treatment of rheumatoid arthritis is described. Stage 1 includes antigen-dependent cultural selection of patient's T cells and stage 2 consists in their reproduction in the needed amounts by nonspecific mitogenic stimulation. T cell vaccination induces an effective specific anti-idiotypic immune response against T cells reactive to joint antigens.

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