Publications by authors named "D M Rapoport"
Respiratory interventions including noninvasive ventilation, continuous positive airway pressure and high-flow nasal oxygen generated infectious aerosols may increase risk of airborne disease (SARS-CoV-2, influenza virus) transmission to healthcare workers. We developed and tested a prototype portable UV-C device to sterilize high flows of viral-contaminated air from a simulated patient source at airflow rates of up to 100 l/m. Our device consisted of a central quartz tube surrounded 6 high-output UV-C lamps, within a larger cylinder allowing recirculation past the UV-C lamps a second time before exiting the device.
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- In patients with obstructive sleep apnea (OSA) undergoing continuous positive airway pressure (CPAP) treatment, the apnea hypopnea index (AHI) generally decreases compared to pre-treatment levels, especially in those with severe OSA.
- The study aimed to identify whether the decrease in AHI is primarily linked to improvements in estimated ventilatory control stability (loop gain, LG) or other physiological factors.
- After analyzing polysomnography data from participants, the researchers concluded that while there was a general decrease in AHI, significant changes in LG and upper airway collapsibility were linked to AHI improvements, particularly in those with severe OSA.
Respiratory interventions including noninvasive ventilation, continuous positive airway pressure and high-flow nasal oxygen generated infectious aerosols may increase risk of airborne disease (SARS-CoV-2, influenza virus) transmission to healthcare workers. We developed/tested a prototype portable UV-C device to sterilize high flows of viral-contaminated air from a simulated patient source at airflow rates of up to 100 l/m. Our device consisted of a central quartz tube surrounded 6 high-output UV-C lamps, within a larger cylinder allowing recirculation past the UV-C lamps a second time before exiting the device.
View Article and Find Full Text PDFBackground: Although related, the precise mechanisms linking obstructive sleep apnea (OSA) and cardiovascular disease (CVD) are unclear. Platelets are mediators of CVD risk and thrombosis and prior studies suggested associations of OSA and platelet activity. The aim of this study is to assess the link between OSA, platelet activity, and CVD-related risk factors.
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