Publications by authors named "D M Pemberton"

Article Synopsis
  • The study evaluated the effectiveness of aticaprant, a medication for major depressive disorder (MDD), in adults who had not adequately responded to previous antidepressant treatment.
  • After a placebo lead-in period, participants received either aticaprant 10 mg or placebo for 6 weeks, with results showing a significant reduction in depression scores for those taking aticaprant compared to the placebo group.
  • Common side effects of aticaprant included headache, diarrhea, and nasopharyngitis, but overall, the treatment was deemed safe, suggesting potential for further research in larger trials.
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Background: To achieve hepatitis C virus (HCV) elimination targets, simplified care engaging people who inject drugs is required. We evaluated whether fingerstick HCV RNA point-of-care testing (PoCT) increased the proportion of clients attending a supervised injecting facility who were tested for hepatitis C.

Methods: Prospective single-arm study with recruitment between 9 November 2020 and 28 January 2021 and follow-up to 31 July 2021.

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Objective: To evaluate the feasibility of testing and treating people who inject drugs at a supervised injecting facility for hepatitis C virus (HCV) infection.

Design: Retrospective cohort study.

Setting, Participants: People who inject drugs who attended the Melbourne supervised injecting facility, 30 June 2018 - 30 June 2020.

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According to 2021 data, the United States' opt-in system of posthumous organ donation results in seventeen Americans dying each day waiting for vital organs, while many good undonated organs go to the grave with the corpse. One of the most aggressive, and compelling, proposals to resolve this tragedy is postmortem organ conscription, also called routine salvaging or organ draft. This proposal entails postmortem retrieval of needed organs, regardless of the prior authorization or refusal of the deceased or his family.

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