Publications by authors named "D M Ouweneel"
Background: Delirium is a severe complication in critical care patients. Accurate prediction could facilitate determination of which patients are at risk. In the past decade, several delirium prediction models have been developed.
View Article and Find Full Text PDFAims: To assess differences in long-term outcome and functional status of patients with cardiogenic shock (CS) treated by percutaneous mechanical circulatory support (pMCS) and intra-aortic balloon pump (IABP).
Methods And Results: Long-term follow-up of the multicentre, randomized IMPRESS in Severe Shock trial (NTR3450) was performed 5-year after initial randomization. Between 2012 and 2015, a total of 48 patients with severe CS from acute myocardial infarction (AMI) with ST-segment elevation undergoing immediate revascularization were randomized to pMCS by Impella CP (n = 24) or IABP (n = 24).
Background: In selected patients with an acute myocardial infarction (AMI) complicated by Cardiogenic shock (CS), mechanical circulatory support with Impella may be beneficial, although conclusive evidence is still lacking. Nevertheless, it has been suggested that Impella initiation prior to primary PCI might improve survival.
Objective: To investigate the effect pre-PCI versus immediate post-PCI Impella initiation on short term mortality.
Article Synopsis
- Vasopressors and inotropes are commonly used to improve blood flow during cardiogenic shock caused by acute myocardial infarction, but their effect on patient mortality is unclear.
- A systematic review of 19 studies, including 2478 patients, indicated that these treatments did not significantly reduce mortality compared to control groups; the quality of evidence was deemed low.
- There was a potential trend showing levosimendan may improve outcomes, but overall, the study suggests more rigorous research is needed to determine the actual impact of these medications on mortality in this patient population.
Article Synopsis
- The study aimed to assess factors influencing the success of percutaneous coronary intervention (PCI) on chronic total occlusions (CTOs) after a heart attack and its effects on heart function and electrical activity.
- It involved data from the EXPLORE trial, categorizing STEMI patients into groups based on the success or failure of the CTO PCI procedure, highlighting that a lesion length greater than 20 mm strongly predicted failure.
- Results indicated that while CTO PCI failures did not significantly impact heart function or pro-arrhythmic ECG parameters after four months, lesion length remained a critical factor in predicting procedural success.