Phase 3 trial of coronavir (favipiravir) in patients with mild to moderate COVID-19.

Favipiravir has demonstrated efficacy against the SARS-CoV-2 virus in several preliminary studies. This study aimed to evaluate the efficacy and safety of favipiravir for treatment of mild to moderate COVID-19 in outpatients and hospitalized patients. We conducted an open-label, randomized, active-controlled trial of a generic form of favipiravir in patients with COVID-19 confirmed by PCR-test.

[The rhinophyma through the prism of time].

One of the frequent causes of a significant increase in the external nose, forming a persistent deformity of the face, as well as leading to a non-standard clinical picture is rhinophyma disease. The article considers some historical data, epidemiology, peculiarities of pathogenesis, as well as the basics of surgical treatment tactics along with possible preventive measures against rhinophyma. At present, the treatment of this pathology presents great difficulties.

[Foreign bodies of the esophagus in children].

Objective: Of this study is to determine the optimal algorithm for active verification and treatment of children with foreign bodies of the esophagus, analysis of the causes and development of related complications.

Patients And Method: The results of examination and treatment of 320 children with foreign bodies of the esophagus for the period from 2011 to 2017 were analyzed. The vast majority of patients (79.

[The foreign body in the larynx in a year old child].

The purpose is: description of clinical observation - successful removal of a foreign body (diode lamp) from the larynx in a child aged one year. Despite the large size of the aspirated object and its localization at the level of the glottis child is breathing through the natural airway. The foreign body was removed through natural ways, with direct laryngoscopy, avoiding the complications.

[An open safety pin in the oesophagus of an one-year old child].

The objective of the present work was the description of the observations documented in the clinical practice concerning the cases of detection of the foreign bodies in the internal organs of human patients. This publication is devoted to the case of the child's accidental swallowing the safety pin. The presence of the open safety pin in the esophagus of the one-year-old child created a serious threat to its health.