Urinary findings and renal function in adult Navajo Indians and associations with type 2 diabetes.

We screened a sample of adult Navajo Indians for signs of renal disease that might underlie their increasing rates of renal failure. Nondiabetics had modest rates of hypertension, which was more common in males and increased with age. Microscopic hematuria was very common, and only a fraction was associated with progressive nephropathy.

Cardiovascular disease in Navajo Indians with type 2 diabetes.

Rates of both type 2 diabetes and cardiovascular disease have risen sharply in recent years among Navajo Indians, the largest reservation-based American Indian tribe, but the association between the two conditions is not entirely clear. Rates of cardiovascular disease and some possible associations in several hundred diabetic and non-diabetic Navajos were estimated. Nearly one-third (30.

Blood pressure in Navajo Indians and its association with type 2 diabetes and renal and cardiovascular disease.

In mid-1990 we evaluated blood pressure and its associations in 366 nondiabetic adult Navajos and 400 Navajos with type 2 diabetes attending Indian Health Service outpatient clinics in Tuba City, Arizona. In nondiabetics, systolic blood pressure (SBP) rose with increasing age while diastolic blood pressure (DBP) fell; 13.4% had hypertension by diagnosis or treatment.

Mesangial proliferative glomerulonephritis in southwestern American Indians.

A series of 166 American Indian renal biopsy specimens from 1971 to 1989 showed a very high proportion with mesangial proliferative glomerulonephritis with mesangial immunoglobulin deposition (Ig-pos mesGN). This disease comprised 68.7% of all the biopsies and 83.