Publications by authors named "D M Lopategui"
Purpose: To compare outcomes of transurethral resection of the prostate (TURP) across different regions worldwide over the past two decades.
Methods: A systematic review and meta-analysis of randomized clinical trials indexed to PubMed that assessed TURP. A total of 102 studies with 8,454 patients were included and grouped by continents: Europe, Asia, Africa, and Others (North America, South America, and Australia).
Introduction: Water Jet Ablation Therapy (WJAT) and Holmium Laser Enucleation of the Prostate (HoLEP) represent two common surgical treatments for Benign Prostatic Hyperplasia (BPH). Despite their increasing use, there is no study between these two methods. We aim to evaluate their efficacy and safety through a network meta-analysis (NMA), providing critical insights for clinical decision-making in the management of moderate to severe lower urinary tract symptoms (LUTS) due to BPH.
View Article and Find Full Text PDFPurpose: The goal of this systematic review is to assess the temporal changes in outcomes and complications of transurethral resection of the prostate (TURP) from 2000 to 2022.
Methods: We conducted a systematic review and meta-analysis of 103 randomized clinical trials from PubMed on TURP, involving 8521 patients. Studies were grouped by years: 2000-2004, 2005-2009, 2010-2014, and 2015-2022.
Article Synopsis
- Open simple prostatectomy (OSP) is still an important treatment for benign prostatic hyperplasia (BPH) in patients with large prostate volumes (>80 ml), especially when compared to newer methods like minimally invasive simple prostatectomy (MISP) and laser enucleation.
- A meta-analysis of 10 randomized controlled trials showed that while OSP significantly improves voiding symptoms, it has a higher risk of postoperative complications such as bleeding and transfusions.
- Although OSP remains a viable treatment option, its higher morbidity rates necessitate careful patient selection and ongoing research to enhance surgical techniques and overall outcomes.