Publications by authors named "D M Hyman"
Article Synopsis
- Patient safety science has changed a lot over the last 70 years with four frameworks: Safety-0, Safety-1, Safety-2, and Safety-3, which help understand how to keep patients safe better.
- In Safety-0, the focus is on preventing harm by improving staffing and education, while Safety-1 looks at both individual mistakes and system failures to create safer hospitals.
- Safety-2 and Safety-3 go further by emphasizing how doctors can adapt to changes and designing systems that help prevent harm, making the care process safer for patients.
Bullous pemphigoid (BP) is an autoimmune skin disorder that causes fluid-filled blisters to appear on various body parts, often preceded by urticaria and pruritis. This case report describes the perifollicular melanocyte regeneration within diseased areas in a skin of color patient with BP. By reviewing the various pathologies that can result in melanocyte destruction and the basic science of melanocyte regeneration, we can better identify and explain this phenomenon to patients and lead to earlier diagnoses.
View Article and Find Full Text PDFPurpose: NCI-MATCH assigned patients with advanced cancer and progression on prior treatment, based on genomic alterations in pretreatment tumor tissue. Arm J (EAY131-J) evaluated the combination of trastuzumab/pertuzumab (HP) across HER2-amplified tumors.
Patients And Methods: Eligible patients had high levels of HER2 amplification [copy number (CN) ≥7] detected by central next-generation sequencing (NGS) or through NCI-designated laboratories.