Publications by authors named "D M Hsieh"
Article Synopsis
- Nonspecific low back pain is common, and the study evaluated the effectiveness of electroacupuncture compared to standard and manual needling therapies through a systematic review and meta-analysis of existing research.
- Out of the 10 included studies, electroacupuncture combined with standard therapy showed a significant reduction in pain compared to standard treatment alone, with a large effect size (SMD -0.83), while no significant difference was found when comparing it to manual needling (SMD 0).
- Despite promising results, the review noted limitations like a small number of studies and participants, indicating a low certainty of evidence, suggesting that further and more rigorous research is necessary.
Sodium carboxymethyl cellulose (CMC-Na), derived from natural cellulose and frequently employed as a biocompatible coating, thus renders it an ideal component for the construction of highly biocompatible neuromorphic devices aimed at biomachine interfaces. Here, an array of Mo/CMC-Na/ITO neuromorphic devices is fabricated, with CMC-Na serving as the functional layer. The devices exhibit capabilities to emulate various synaptic learning rules and demonstrate high endurance performance among biomaterial-based electronics, achieving stability over 2 × 10 pulses.
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- Glioblastoma is an aggressive brain cancer that currently lacks effective treatments, prompting research for better therapeutic options.
- Researchers discovered a compound called gliocidin that selectively kills glioblastoma cells without harming normal cells by targeting a specific vulnerability in the cancer's purine synthesis process.
- Gliocidin works by being converted into an active metabolite that disrupts cancer cell metabolism, and when combined with the drug temozolomide, it shows potential for enhancing patient survival rates in animal models.
Neuromorphic bioelectronics aim to integrate electronics with biological systems yet encounter challenges in biocompatibility, operating voltages, power consumption, and stability. This study presents biocompatible neuromorphic devices fabricated from acellular dermal matrix (ADM) derived from porcine dermis using low-temperature supercritical CO extraction. The ADM preserves the natural scaffold structure of collagen and minimizes immunogenicity by eliminating cells, fats, and noncollagenous impurities, ensuring excellent biocompatibility.
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- * The study investigated the potential protective effects of water-extracted Artemisia argyi (AA) on heart cells (H9c2) exposed to DOX, focusing on specific cellular signaling pathways (IGF-IIR/Drp1/GATA4).
- * Results indicated that AA extract not only reduced damage caused by DOX but also mitigated symptoms of cardiac toxicity, suggesting it could be a promising option to protect the heart during cancer treatment.