Strain Expressed Constitutively High Levels of Sterol 14-α Demethylase mRNA, While Transporter and mRNA Expression Was Induced After Addition of Short Chain Azoles.

is an emerging pathogen causing recalcitrant skin infections and exhibiting multiple resistances to azoles and allylamines. Squalene epoxidase mutants often show association with azole resistance. RT-PCR gene expression analysis helps to elucidate the connection between ergosterol biosynthesis regulation and efflux control through the activation of multidrug resistance (MDR) and major facilitator superfamily (MFS1) transporters as well as heat shock proteins (HSP).

Cream versus ointment: Randomized single-blinded study on the adherence to treatment with topical methylprednisolone aceponate.

Background: Overall adherence in the treatment of chronic dermatoses is poor. Textbooks state an adherence dependence on galenics.

Trial Design: Prospective, randomized, parallel-grouped, single-blinded (investigator), monocentric clinical trial (phase IV) on the adherence to treatment of chronic mild to moderate hand eczema with topical methylprednisolone aceponate (MPA, Advantan®) in different vehicles.

Ethnic diversity in German dermatology textbooks: Does it exist and is it important? A mini review.

Recently published research has detected discrepancies in medical care as a result of skin color in Anglo-American countries. This was partly attributed to the fact that medical and dermatological specialist training textbooks were found to consist of examples and material that could be classified as more than 90 % white and fair skin (Fitzpatrick's skin types I-III), including pictures in textbooks and scientific literature used as standard reference works. This systematic review reveals similar findings for German dermatological textbooks and consequently gives rise to the question of whether current medical training and practice in Germany adequately meets the needs of a population that is becoming ever more diverse.