Publications by authors named "D M Fiore"
Plastic pollution is a global problem affecting the environment and, consequently, people's well-being. Careful and timely end-of-life plastic recycling is certainly a way, albeit a partial one, to remedy the problem. The immediate identification and selection of the different types of plastic materials in the recycling process certainly facilitate its recovery and reuse, allowing the damage caused by plastic emission into the environment to be limited.
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- Carob (Ceratonia siliqua) leaves were studied for their chemical makeup and health benefits, focusing on making carob farming more sustainable.
- Key components identified in the leaves include various types of galloylated glucoses and flavonol-glycosides, with high levels of bioactive compounds linked to antioxidant properties.
- The leaves showed strong inhibitory effects on enzymes related to diabetes and neurodegenerative diseases, suggesting they may help manage blood sugar levels with minimal side effects.
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- Longer periods between headache episodes may allow the nervous system to recover better, possibly enhancing patients' quality of life and disease status.
- The study, PROMISE-2, analyzed data from over 1,000 chronic migraine patients to examine the relationship between the length of interictal periods (time between headaches) and various patient-reported health outcomes.
- Results showed that patients with interictal periods longer than 21 days reported significantly better improvements in headache impact, overall health status, and bothersome symptoms compared to those with shorter periods.
In this study, the structural attributes of nanoparticles obtained by a renewable and non-immunogenic "inulinated" analog of the "pegylated" PLA (PEG-PLA) were examined, together with the potential of these novel nanocarriers in delivering poorly water-soluble drugs. Characterization of INU-PLA assemblies, encompassing critical aggregation concentration (CAC), NMR, DLS, LDE, and SEM analyses, was conducted to elucidate the core/shell architecture of the carriers and in vitro cyto- and hemo-compatibility were assayed. The entrapment and in vitro delivery of sorafenib tosylate () were also studied.
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- Silicon Photomultipliers (SiPMs) are compact and efficient single photon detectors that are becoming popular in space applications due to their advantages over traditional photomultiplier tubes, especially in low-power and weight-constrained environments.
- Exposure to high levels of radiation during space missions can negatively impact SiPM performance, prompting research into understanding and improving their radiation damage effects.
- The study involved irradiating small area NUV-HD SiPMs and showed that proton damage primarily increases dark count rates, but smaller devices demonstrated better resilience, suggesting future designs could focus on light or charge-focusing mechanisms for enhanced radiation tolerance.