Publications by authors named "D M D'Ugo"

Background: Esophageal perforation or postoperative leak after esophageal surgery remain a life-threatening condition. The optimal management strategy is still unclear.

Aim: To determine clinical outcomes and complications of our 15-year experience in the multidisciplinary management of esophageal perforations and anastomotic leaks.

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: The textbook outcome (TO) is a composite tool introduced to uniform surgical units and regulate surgical quality and outcomes. A patient is considered TO only if all predetermined items are met. In colorectal surgery, TO represents a new tool that can achieve important results given the prevalence of colorectal cancers.

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Article Synopsis
  • Various anastomotic and reconstruction techniques were assessed in patients undergoing minimally invasive total (miTG) and distal gastrectomy (miDG) to understand their impact on postoperative complications.
  • A study involving over 4,200 patients found that miTG had significantly higher rates of complications like anastomotic leakage and overall morbidity compared to miDG.
  • The findings suggest that miDG is preferable for patients needing surgery, while linear stapled techniques should be favored in miTG to minimize risks.*
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  • Clostridium difficile infection (CDI) can occur after stoma reversal surgery, and this systematic review evaluated its incidence and potential risk factors.* ! -
  • The review analyzed 43 studies, including a total of 17,857 patients, finding a CDI incidence of 2.1%, with no significant differences in age or sex between infected and non-infected patients.* ! -
  • A correlation was identified between CDI and the use of neo-adjuvant and adjuvant therapies, with adjuvant therapy showing a possible increased risk of CDI.* !
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Article Synopsis
  • - Gastro-esophageal cancers (GECs) are serious illnesses with rapidly evolving management techniques, and the European Society of Surgical Oncology (ESSO) is focused on enhancing knowledge in this area through a multidisciplinary approach.
  • - The review covers various aspects of GEC management, including oligometastatic cancers, peritoneal metastases, Siewert Type II tumors, robotic surgery, and the use of molecular markers and immune therapies.
  • - The goal is to provide an updated overview of GEC management practices, highlight recent advancements, and promote discussions among surgical oncologists globally, benefiting both seasoned and training professionals in the field.
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