Publications by authors named "D M Chisholm"

Background: Access to effective treatment for major depressive disorder remains limited and difficult to track across place and time. We analysed the available data on minimally adequate treatment (MAT) for major depressive disorder globally with the aim of providing a useful metric against which to monitor national responses to the growing public health burden imposed by major depressive disorder.

Methods: MAT was defined as pharmacotherapy (1 month of medication, plus four visits to a medical doctor) or psychotherapy (eight visits with any professional).

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Introduction: Community partnership is a key strategy for addressing the social determinants of health and achieving health equity. There are few examples of curricula for undergraduate medical education that teach all, rather than self-selected, medical students to collaborate with community members to improve health. We describe the design and implementation of the Community Health Advocacy Initiative (CHAI) curriculum, a new yearlong educational program for medical students at Northwestern University's Feinberg School of Medicine.

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Article Synopsis
  • The emergence of antibiotic resistance is a major health concern, creating a need for new treatments.
  • A newly identified fluorescent photoactivatable diarylacetylene has shown strong antibacterial effects specifically against Gram-positive bacteria, while Gram-negative bacteria are more resistant due to their protective outer membrane.
  • The antibiotic's mechanism involves generating reactive oxygen species, and it may be especially useful for treating skin infections.
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