Publications by authors named "D M Cella"
Early life environmental exposures, even those experienced before conception, can shape health and disease trajectories across the lifespan. Optimizing the detection of the constellation of exposure effects on a broad range of child health outcomes across development requires considerable sample size, transdisciplinary expertise, and developmentally sensitive and dimensional measurement. To address this, the National Institutes of Health (NIH) Environmental influences on Child Health Outcomes (ECHO) Cohort Study is an observational longitudinal pediatric cohort study.
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- The study focused on evaluating the effects of tofacitinib on fatigue in patients with ankylosing spondylitis (AS) through a phase 3 randomized controlled trial.
- Results showed that patients taking tofacitinib experienced a faster improvement in fatigue symptoms compared to those on a placebo, with significant percentages achieving noticeable relief within 16 weeks.
- The findings suggest that tofacitinib may be an effective treatment option for quickly alleviating fatigue in AS patients, providing healthcare providers with valuable information when discussing treatment plans with their patients.
Objective: Cancer-specific psychological interventions like cognitive behavioral stress management (CBSM) demonstrate distress (e.g., anxiety/depression) and quality of life (QoL) benefits.
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- Researchers explored web-based survey options, comparing the costs and data quality of a convenience panel (MTurk) with a probability-based panel (KnowledgePanel), highlighting the trade-offs between cost and data integrity.
- The study utilized the same survey administered to both panels, implementing quality assurance steps for MTurk while KnowledgePanel followed standard protocols, ultimately examining the effectiveness of each in providing reliable data.
- Findings indicated the importance of prescreening to improve the quality of MTurk data, showing variations in response accuracy and representativeness between the two platforms.