Publications by authors named "D M Candido"
Article Synopsis
- Western equine encephalitis virus (WEEV) caused a significant outbreak in Argentina and Uruguay from December 2023 to April 2024, with 217 human cases and 2,548 equine cases reported.
- The investigation focused on the Rio Grande do Sul state border area between Argentina and Uruguay, utilizing epidemiologic, entomological, and genomic methods to analyze the outbreak.
- A novel lineage of the virus, proposed as lineage C, was identified in three fatal equine cases, emphasizing the need for ongoing monitoring and equine vaccination to prevent future outbreaks.
Article Synopsis
- Chikungunya virus (CHIKV) can lead to severe diseases, including chronic arthritis and, in rare cases, neurological issues and death, primarily transmitted by mosquitoes.
- A comprehensive study revealed that deaths from CHIKV are linked to multi-organ infections, serious brain damage, and higher levels of inflammation in the body compared to survivors.
- The research also found that CHIKV infection disrupts the blood-brain barrier, leading to increased permeability and changes in protein expression, enhancing our understanding of CHIK pathophysiology and fatal outcomes.
Magnon-mediated qubit coupling determined via dissipation measurements.
Proc Natl Acad Sci U S A
January 2024
Controlled interaction between localized and delocalized solid-state spin systems offers a compelling platform for on-chip quantum information processing with quantum spintronics. Hybrid quantum systems (HQSs) of localized nitrogen-vacancy (NV) centers in diamond and delocalized magnon modes in ferrimagnets-systems with naturally commensurate energies-have recently attracted significant attention, especially for interconnecting isolated spin qubits at length-scales far beyond those set by the dipolar coupling. However, despite extensive theoretical efforts, there is a lack of experimental characterization of the magnon-mediated interaction between NV centers, which is necessary to develop such hybrid quantum architectures.
View Article and Find Full Text PDFSkull base chrodomas are slow growing neoplasms usually located along the midline. They display a locally invasive nature with possibilities of extracranial metastasis. Presentation is usually late and depends upon the location and extent of the tumour.
View Article and Find Full Text PDFBackground And Aims: Developing novel therapies to battle the global public health burden of heart failure remains challenging. This study investigates the underlying mechanisms and potential treatment for 4-hydroxynonenal (4-HNE) deleterious effects in heart failure.
Methods: Biochemical, functional, and histochemical measurements were applied to identify 4-HNE adducts in rat and human failing hearts.