Publications by authors named "D M Arman"
Background: We aimed to evaluate the effects of minimal enteral nutrition (MEN) on mesenteric blood flow and oxygenation with Doppler USG and Near Infrared Spectroscopy (NIRS) during therapeutic hypothermia (TH) in babies with HIE.
Methods: This prospective, randomized-controlled study was composed of infants receiving MEN (study group, n = 30) and infants who were not fed (control group, n = 30) during hypothermia. Infants were monitored continuously with NIRS and mesenteric blood flow velocities were measured with Doppler USG before and after feeding.
Article Synopsis
- The study explores how arsenic exposure in parents, particularly fathers, may affect DNA methylation in infants with spina bifida, suggesting a link between environmental toxins and genetic changes.
- Researchers analyzed arsenic levels in fathers' toenails and measured DNA methylation in various tissues from infants, finding a significant association in dural tissue.
- The findings highlight the relevance of these epigenetic changes, particularly in pathways related to neural development, and underscore the need for further research on paternal exposure to toxins.
Article Synopsis
- Spina bifida is a neural tube defect linked to genetic and environmental factors, specifically maternal arsenic exposure, which affects fetal development during pregnancy.
- The study analyzed data from 262 mothers and 220 infants in Bangladesh to explore the relationship between maternal arsenic levels and spina bifida risk, focusing on specific genetic variations in folate and arsenic metabolism.
- Results indicated that certain single-nucleotide polymorphisms (SNPs) related to arsenic metabolism in infants and mothers significantly increased the likelihood of spina bifida when combined with high arsenic exposure.
Background: Spina bifida, a developmental malformation of the spinal cord, is associated with high rates of mortality and disability. Although folic acid-based preventive strategies have been successful in reducing rates of spina bifida, some areas continue to be at higher risk because of chemical exposures. Bangladesh has high arsenic exposures through contaminated drinking water and high rates of spina bifida.
View Article and Find Full Text PDFObjective: Reports on the management and survival of children with myelomeningocele defects in Bangladesh are limited. This study describes the characteristics and outcomes of these children, focusing on the timing of surgical repair and factors affecting survival.
Methods: We enrolled patients with myelomeningoceles in a case-control study on arsenic exposure and spina bifida in Bangladesh.