Publications by authors named "D Lynn Loriaux"
Article Synopsis
- Calcium channel blockers (CCBs) are used to treat various conditions like high blood pressure and heart issues, with nimodipine being effective in protecting hearing after certain surgeries.
- A case report describes a 56-year-old woman with severe liver disease who experienced dangerous vasodilatory shock after taking nimodipine for surgery recovery.
- The report aims to raise awareness about the heightened risk of CCB toxicity in patients with advanced liver dysfunction when given nimodipine during the perioperative period.
Article Synopsis
- The study examines the characteristics and outcomes of adult congenital heart disease (ACHD) patients admitted to cardiac intensive care units (CICUs) in North America from 2017 to 2022, revealing limited previous knowledge in this area.
- Out of 23,299 CICU admissions, only 441 (1.9%) were for ACHD, which tended to be younger patients who had more admissions related to heart failure and medical issues compared to non-ACHD patients.
- Despite longer hospital stays for ACHD patients, their in-hospital mortality rates were similar to those of non-ACHD patients, indicating the need for more focused research on managing specific complexities related to ACHD in the CICU.*
Clinical practice in the contemporary cardiac intensive care unit (CICU) has evolved significantly over the last several decades. With more frequent multisystem organ failure, increasing use of advanced respiratory support, and the advent of new mechanical circulatory support platforms, clinicians in the CICU are increasingly managing patients with complex comorbid disease in addition to their high-acuity cardiovascular illnesses. Here, the authors discuss challenges associated with traditional trial design in the CICU setting and review novel clinical trial designs that may facilitate better evidence generation in the CICU.
View Article and Find Full Text PDFPrognostic significance of haemodynamic parameters in patients with cardiogenic shock.
Eur Heart J Acute Cardiovasc Care
October 2023
Article Synopsis
- Invasive haemodynamic assessment using a pulmonary artery catheter is important for managing patients with cardiogenic shock (CS) and understanding their prognosis.
- A study analyzed data from a multicenter registry involving patients with CS to find relationships between their haemodynamic parameters and outcomes like in-hospital mortality and end-organ dysfunction.
- Key findings indicated that lower mean arterial pressure, lower systolic blood pressure, and other specific haemodynamic metrics were linked to worse outcomes and higher serum lactate levels, suggesting severe circulatory issues.
There is limited large, national data investigating the prevalence, characteristics, and outcomes of cardiac arrest (CA) in patients hospitalized for heart failure (HF). The goal of this study was to examine the characteristics, trends, and outcomes of HF hospitalizations complicated by in-hospital CA. We used the National Inpatient Sample to identify all primary HF admissions from 2016 to 2019.
View Article and Find Full Text PDF