Publications by authors named "D Lupoi"
The COVID-19 pandemic has led to the emergence of post-acute COVID-19 syndrome, also known as long COVID, which presents a significant challenge due to its varied symptoms and unpredictable course, particularly in older adults. Similar to COVID-19 infections, factors such as age, pre-existing health conditions, and vaccination status may influence the occurrence and severity of long COVID. The objective is to analyze the role of aging in the context of long COVID and to investigate prevalence rates and vaccination efficacy to improve prevention strategies and treatment in this age group.
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- Odontogenic maxillary sinusitis (OMS) is an infection linked to dental issues that can lead to dangerous eye and orbital complications due to the close anatomical relationships in the area.
- A study of 18 patients with OMS and associated complications revealed a range of co-existing medical conditions, with diabetes being a significant risk factor, and highlighted that 10 patients had preseptal cellulitis while 8 had orbital cellulitis.
- Treatment for severe cases often involves urgent broad-spectrum antibiotics and sometimes surgery, with positive outcomes for those who underwent surgical procedures, although complications like loss of vision may arise especially when symptoms affect both eyes.
Sepsis causes immune dysregulation and endotheliitis, with an increase in mid-regional pro-adrenomedullin (MR-proADM). The aim of the study is to determine an MR-proADM value that, in addition to clinical diagnosis, can identify patients with localized infection or those with sepsis/septic shock, with specific organ damage or with the need for intensive care unit (ICU) transfer and prognosis. The secondary aim is to correlate the MR-proADM value with the length of stay (LOS).
View Article and Find Full Text PDFBILATERAL CAROTID BODY PARAGANGLIOMAS - LITERATURE REVIEW AND COMMENTS IN A PATIENT WITH NO SIGNS OF MEN SYNDROME.
Acta Endocrinol (Buchar)
August 2023
Unlabelled: Paragangliomas are rare neuroendocrine slow-growing tumors, often asymptomatic, that originate from embryonic neural crest cell. In the head and neck area, the most common location is the carotid body, followed, with decreasing frequency, in jugular, tympanic and vagal sites. Bilateral carotid body tumors are extremely rare.
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- The study investigates the relationship between mid-regional proAdrenomedullin (MR-proADM) levels and myocardial injury in COVID-19 patients, aiming to predict mortality outcomes.
- Conducted at a COVID-19 Center in Rome, the study analyzed 161 hospitalized patients, defining myocardial injury through elevated cardiac hs Troponin I levels.
- Results showed that 36% of patients had myocardial injury, with a significantly higher mortality rate in this group (46.6%) compared to those without injury (6.8%), indicating MR-proADM could serve as a useful prognostic biomarker.