Publications by authors named "D Luk"

Article Synopsis
  • The study updated asthma and wheezing data for children in Hong Kong, comparing it to results from earlier ISAAC studies conducted in the mid-1990s and early 2000s.
  • Data was collected from over 2,000 children aged 6-7 and 13-14 between September 2020 and August 2021, using standardized protocols to analyze sex differences and risk factors for asthma severity.
  • Results showed a decrease in asthma prevalence and severity since the previous studies, with follow-up research planned to delve into protective and risk factors contributing to these changes.
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Fish allergy is a significant health concern, with diagnosis and management complicated by diverse fish species and allergens. We conducted a comprehensive RNA-seq analysis of eight fish species to identify allergen profiles, integrating ImmunoCAP sIgE data to explore associations with allergen expression and diagnostic performance. Over 30 putative fish allergens were identified, with varying sequence similarities and expression levels, roughly classifying fish into two groups based on parvalbumin (PV) expression.

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Unlabelled: WHAT IS KNOWN ON THE SUBJECT?: Mental health care can be delivered remotely through video and telephone consultations. Remote consultations may be cheaper and more efficient than in person consultations.

What The Paper Adds To Existing Knowledge: Accessing community mental health care through remote consultations is perceived as not possible or beneficial for all service users.

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Artificial intelligence has demonstrated a promising potential for diagnosing complex medical cases, with Generative Pre-Trained Transformer 4 (GPT-4) being the most recent advancement in this field. This study evaluated the diagnostic performance of the GPT-4 in comparison with that of its predecessor, GPT-3.5, using 81 complex medical case records from the New England Journal of Medicine .

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Article Synopsis
  • Seafood allergy is a significant risk, particularly in early childhood, with limited real-world data on its clinical presentation.* -
  • A study involving 249 fish-allergic participants in Hong Kong revealed that 30% reacted to certain fish; a notable finding was the varying tolerance levels depending on the fish's β-parvalbumin content.* -
  • The results indicate that many individuals with fish allergies can tolerate certain fish and types of shellfish, highlighting the need for more tailored approaches in managing seafood allergies.*
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