Erythrophagocytosis++ test was performed in 45 pregnant Rh-negative women together with routine anti-Rh antibodies assay with indirect antiglobulin test and their concentration determined in an autoanalyser. It was found that the degree of ++phagocytosis of the standard erythrocytes immunized with maternal anti-Rh antibodies by the monocytes from healthy subjects is an important predictive factor enabling to foresee a severity of hemolytic disease in newborn babies. ++Phagocytosis over 50% predicts a severe course of the disease whereas under 20%--a mild form of the serologic conflict.
View Article and Find Full Text PDFThe authors analysed perinatal mortality and the condition of 32 newborns of 30 pregnant women with a severe form of gestosis EPH, who did not react to therapy. In all the women the pregnancy was terminated prematurely between 29th and 37th week (not later than 7 days admission to hospital) because of threat to the fetus, threat to the pregnant woman due to renal failure or threat both to the fetus and the woman. In spite of the fact that the newborns had a lower birth weight in comparison with newborns born in the previous years, the above procedure led to the sixfold reduction of perinatal mortality.
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