Publications by authors named "D Lopez Otero"

The extraction of bioactive compounds from cacti using green methods holds promise as an area of research that remains relatively underexplored. This review aims to summarize findings and trends in this field, assessing the effectiveness of green techniques applied to these unique plants. Among the green methods, Ultrasound-Assisted Extraction (UAE) stands out as the most extensively studied, consistently yielding a higher extraction of compounds irrespective of the duration and solvents employed.

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The development of technologies that allow the production of enzymes at a competitive cost is of great importance for several biotechnological applications, and the use of agro-industrial by-products is an excellent alternative to minimize costs and reduce environmental impacts. This study aimed to produce endo-xylanases using agro-industrial substrates rich in hemicellulose as sources of xylan in culture media. For this purpose, the yeast Cryptococcus laurentti and five lignocellulosic materials (defatted rice bran, rice husk, corn cob, oat husks, and soybean tegument), with and without pretreatment, were used as a source of xylan for enzyme production.

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Background: Guidelines recommend shared decision making when choosing treatment for severe aortic stenosis but implementation has lagged. We assessed the feasibility and impact of a novel decision aid for severe aortic stenosis at point-of-care.

Methods: This prospective multi-site pilot cohort study included adults with severe aortic stenosis and their clinicians.

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Background: The current available evidence on the management of metastatic renal cell cancer (mRCC) in real life is scarce in our environment. We present a summary of the existing real-world data and the results of an analysis describing the clinical characteristics, treatments, and health outcomes of patients with mRCC in northern Spain.

Methods: Retrospective observational study.

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Phenolic compounds were extracted from biphasic olive pomace and their biological potential was characterised. Two different extracts were prepared, E1 (40% methanol) and E2 (80% methanol), both subjected to agitation (180 min) and 70 °C. LC-ESI-qTOF-MS was used for individual quantification of the extracted phenolic compounds.

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