Publications by authors named "D Lindholm"

This perspective piece addresses the challenges junior clinician-educators face as they navigate career development within academic medical centers. In addition to understanding local promotion and tenure processes and seeking mentorship, we argue that faculty feedback is an often neglected, but essential, component in clinician-educator development. We repurpose and use the MISCA model-Message, Implementation, Student, Context, and Agents-as a framework to better understand and improve feedback for faculty.

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  • A study investigated the relationship between COVID-19 vaccination and the risk of developing venous thrombosis or embolism (VTE) after infection, particularly examining the impact of booster shots.
  • The research analyzed data from Military Health System beneficiaries who tested positive for COVID-19 between 2020 and 2022, finding that vaccinated individuals had significantly lower odds of developing VTE compared to those unvaccinated.
  • Results indicated that the risk of post-COVID-19 VTE was particularly low during the Omicron variant era, and those receiving booster shots had an even greater reduction in VTE risk.
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Unlabelled: Antigen-based rapid diagnostic tests (Ag-RDTs) provide timely results, are simple to use, and are less expensive than molecular assays. Recent studies suggest that antigen-based testing aligns with virus culture-based results (a proxy of contagiousness at the peak viral phase of illness); however, the performance of Ag-RDTs for newer SARS-CoV-2 variants is unclear. In this study, we (i) assessed the performance of Ag-RDTs and diagnostic antibodies to detect a range of SARS-CoV-2 variants and (ii) determined whether Ag-RDT results correlated with culture positivity.

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  • The study examined 595 SARS-CoV-2 sequences from Military Health System beneficiaries to assess how vaccination affected viral diversity from December 2020 to April 2022.
  • Results indicated that vaccination had limited influence on the diversity of the SARS-CoV-2 spike protein and showed little evidence of a significant sieve effect among major variants.
  • The findings suggest that during periods of rapid variant replacement, other factors overshadowed the influence of vaccination on viral diversity, and caution is needed when using sieve analysis methods in non-clinical trial settings.
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