Publications by authors named "D Limmathurotsakul"
Antimicrobial resistance (AMR) is predicted to outstrip malaria, HIV, and tuberculosis combined as the leading infectious cause of death by 2050. Strengthening the knowledge and evidence base for AMR with surveillance and research is one of the five main objectives of the WHO Global Action Plan on AMR. While recent efforts to strengthen diagnosis and surveillance have been encouraging, these are unlikely to be sustainable without continued funding support in most low-resource settings.
View Article and Find Full Text PDFBackground: There is an urgent need to understand the implementation barriers of antimicrobial stewardship programmes (ASPs) in low- and middle-income countries.
Methods: We conducted a mixed-methods study in public and private hospitals across all provinces in Indonesia (March-December 2023). We used a self-assessment questionnaire with a scoring system, and multi-level ordinal regression to assess associations with hospital and district-level characteristics.
Objectives: To evaluate the frequency of antimicrobial-resistant bloodstream infections (AMR BSI) in Thailand.
Methods: We analyzed data from 2022, generated by 111 public hospitals in health regions 1 to 12, using the AutoMated tool for Antimicrobial resistance Surveillance System (AMASS), and submitted to the Ministry of Public Health, Thailand. Multilevel Poisson regression models were used.
Article Synopsis
- Melioidosis is a serious infection caused by a bacteria called Burkholderia pseudomallei, often leading to pneumonia or sepsis and high death rates, even with treatment.
- Researchers studied blood samples from patients with melioidosis and found that it activates certain immune responses differently compared to other infections.
- They discovered a set of 5 specific genes that can help predict who is more likely to die from melioidosis, which could improve future treatments and patient care.
Background: The presence of antimicrobial-resistant (AMR) bacteria in edible ice in tropical countries is largely unknown.
Methods: We evaluate the presence of extended-spectrum β-lactamase (ESBL)-producing Enterobacterales in 100 edible ice samples from drink carts in 20 markets in four provinces (five markets/province) in Thailand. Ten samples of commercially sold edible ice in sealed packages were tested as controls.