Publications by authors named "D Lill"

Background: Omega-3 fatty acids (ω-3 FA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), are essential nutrients known for their anti-inflammatory properties, which involve reducing pro-inflammatory cytokines, eicosanoids, and insulin-like growth factor-1. This suggests their potential to alleviate acne severity, especially when deficits are present.

Aims: To elevate EPA/DHA levels in acne patients through dietary intervention and supplementation, observing subsequent clinical effects.

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Omega-3 fatty acids (ω-3 FAs) exert anti-inflammatory effects, including the downregulation of pro-inflammatory cytokines, eicosanoids, and insulin-like growth factor-1. Therefore, they may improve acne severity as an adjunct treatment. However, there is a paucity of data regarding patients' existing deficits.

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Allergen-specific immunotherapy (AIT) is the only causal and disease-modifying treatment for immunoglobulin E (IgE)-mediated type I allergies. Regular exposure to the causative allergen results in an immunomodulatory effect by which the predominant T‑helper (Th) 2 lymphocyte response is shifted to a Th1 lymphocyte response and more allergen-specific blocking immunoglobulins are produced. The approval of substances for AIT is regulated by the Therapy Allergens Ordinance (TAV).

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Article Synopsis
  • The study examines the relationship between certain genetic factors (IL-1β polymorphisms) and the history of allergies in patients experiencing complications after joint replacements, specifically those not caused by infection or mechanical issues.
  • Researchers found that patients with aseptic complications (SA) had a higher rate of metal allergies compared to asymptomatic patients (AA) and a significant association with the IL1RN VNTR allele 498 bp, particularly in individuals with a history of allergies.
  • The findings suggest that the IL1RN allele may increase the risk of symptomatic complications in joint replacement surgeries, especially among those with allergic tendencies.
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