Publications by authors named "D Ligi"
Background: In the Mediterranean basin, three Leishmania species have been identified: L. infantum, L. major and L.
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- SARS-CoV-2 can lead to a range of symptoms from none at all to severe cases like sepsis, prompting interest in how platelet indices relate to COVID-19 severity.
- A systematic review of various studies found that platelet distribution width (PDW) values were significantly higher in COVID-19 patients, indicating potential connections between increased PDW and disease severity or mortality.
- Though many studies suggested a link between elevated PDW levels and severe outcomes, the overall inconsistency in findings means further research is needed to clarify PDW's role as a prognostic biomarker in COVID-19.
Reduction in oxygen levels is a key feature in the physiology of the bone marrow (BM) niche where hematopoiesis occurs. The BM niche is a highly vascularized tissue and endothelial cells (ECs) support and regulate blood cell formation from hematopoietic stem cells (HSCs). While in vivo studies are limited, ECs when cultured in vitro at low O (<5%), fail to support functional HSC maintenance due to oxidative environment.
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