Publications by authors named "D Lehnick"
The choice of modality of treatment for unruptured intracranial aneurysms is based on various clinical aspects and the patient's preference. Financial considerations should not be among these. To evaluate any financial variations between endovascular and microsurgical treatment of unruptured intracranial aneurysms in the Swiss healthcare system, we retrospectively reviewed 100 consecutive aneurysm cases treated as inpatients in our institution.
View Article and Find Full Text PDFIntroduction: Checkpoint inhibitors are increasingly important in anti-cancer treatment. Therefore, knowledge of immune-related cutaneous adverse events (ir-cAE) is crucial for therapy management and continuation.
Objective: The study aimed to analyze the incidence of cutaneous adverse events caused by checkpoint inhibitor therapy, including their clinical presentation, management, and impact on further treatment.
Background: Insufficient 25-hydroxyvitamin D [25(OH)D] levels are associated with falls, fractures, and worse overall health outcomes. We evaluated 25(OH)D levels in individuals with spinal cord injury or disorder (SCI/D) during postacute rehabilitation who received vitamin D3 supplementation according to routine clinical practice. Associations with clinical outcomes were also assessed.
View Article and Find Full Text PDFArticle Synopsis
- Hip fractures in older adults are common and pose serious risks, such as higher morbidity and mortality, especially when preoperative dehydration is not addressed.
- A study at a Swiss trauma center evaluated a goal-directed fluid resuscitation protocol (GDT) in geriatric patients with a high p-POSSUM Score to see if it could lower mortality and complications after surgery for proximal femur fractures.
- Results showed that while the GDT group initially had lower 30-day mortality rates, the trend shifted in later years, and overall, the GDT did not significantly reduce complications compared to standard care.
Background: Early-life antibiotic exposure is disproportionately high compared to the burden of culture-proven early-onset sepsis (CP-EOS). We assessed the contribution of culture-negative cases to the overall antibiotic exposure in the first postnatal week.
Methods: We conducted a retrospective analysis across eleven countries in Europe, North America, and Australia.