What does it mean to feel good? Is our experience of gazing in awe at a majestic mountain fundamentally different than erupting with triumph when our favorite team wins the championship? Here, we use a semantic space approach to test which positive emotional experiences are distinct from each other based on in-depth personal narratives of experiences involving 22 positive emotions ( = 165; 3,592 emotional events). A bottom-up computational analysis was applied to the transcribed text, with unsupervised clustering employed to maximize internal granular consistency (i.e.
View Article and Find Full Text PDFObjective: The purpose of this study was to assess the self-reported depression, anxiety, and stress responses of chiropractors in South Africa during the first year of the COVID-19 pandemic.
Methods: This was an explorative cross-sectional survey. The survey was distributed to 884 chiropractors through the membership databases of the Chiropractic Association of South Africa and the Allied Health Professions Council of South Africa from July 9, 2020, until August 4, 2020.
Infections due to extended-spectrum β-lactamase (ESBL)-producing Enterobacterales are an increasingly common problem. For many of these infections, no oral treatment options are available. The activity of amoxicillin-clavulanate combined with ceftibuten or cefpodoxime was evaluated against a group of and clinical isolates possessing a variety of CTX-M- and SHV-type ESBLs; some possessed bla as well.
View Article and Find Full Text PDFObjectives: Cefiderocol maintains activity against most MDR Gram-negative pathogens including Pseudomonas aeruginosa. In laboratory-derived isolates, down-regulation of TonB-dependent siderophore receptors have been implicated in resistance to cefiderocol.
Methods: In this report, the expression of seven TonB-dependent siderophore receptors was examined in 10 clinical isolates with cefiderocol MICs ranging from ≤0.