Encapsulated Butyric Acid and Zinc as a Feed Additive for Lambs Abruptly Transitioned to a Grain-Based Diet.

Butyric acid is attributed to gastrointestinal epithelial development and health and two studies were conducted to determine if supplementing encapsulated butyric acid and zinc (BZ) in lambs abruptly transitioned to a finishing diet has effects on growth performance, efficiency of dietary net energy utilization, rumen morphometrics, small intestinal histology, and carcass traits. Polypay wethers (n = 84; initial shrunk body weight = 38.8 kg ± 4.

Controlling CAR-T cell activity and specificity with synthetic SparX adapters.

While conventional chimeric antigen-receptor (CAR)-T therapies have shown remarkable clinical activity in some settings, they can induce severe toxicities and are rarely curative. To address these challenges, we developed a controllable cell therapy where synthetic D-domain-containing proteins (soluble protein antigen-receptor X-linker [SparX]) bind one or more tumor antigens and mark those cells for elimination by genetically modified T cells (antigen-receptor complex [ARC]-T). The chimeric antigen receptor was engineered with a D-domain that specifically binds to the SparX protein via a unique TAG, derived from human alpha-fetoprotein.

The impact of eye movement on postural control depends on the type of oculomotor behavior and the visual task.

Recent evidence suggests that performing a task inducing saccades will improve stability when compared to static fixation. However, they assume the linearity of postural control by only interpreting the area of displacement and/or the velocity of sway. Conversely, non-linear measures could bring a complementary understanding of postural control.

The effect of supplementing CLOSTAT 500 ( PB6) to yearling steers in a commercial feedyard on health, spp. prevalence, feedlot growth performance and carcass characteristics.

British and British × Continental crossbred beef steers, = 2,100; 313 ± 38 kg of initial body weight (BW) were used to evaluate the effects of supplementation to yearling steers in a commercial feedyard on health, prevalence of spp., growth performance, and carcass characteristics. Steers were blocked by arrival date and assigned randomly to pens within the block; pens were randomly assigned to 1 of 2 dietary treatments within block.