Publications by authors named "D L Spriggs"
Article Synopsis
- * A total of 205 patients participated, with a 1-year target-vessel failure (TVF) rate of 7.4%, significantly below the performance goal set at 24.5%, and a 3-year TVF rate of 12.1%.
- * The findings indicate that using a provisional stenting approach for bifurcation lesions with the Resolute Onyx ZES led to positive clinical outcomes, suggesting it
Background: Ovarian cancer remains the deadliest of the gynecologic cancers in the United States. There have been limited advances in treatment strategies that have seen marked increases in overall survival. Thus, it is essential to continue developing and validating new treatment strategies and markers to identify patients who would benefit from the new strategy.
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- * Researchers studied a protein called Galectin 3 (Gal3) to see how it affects USC and found that high levels of Gal3 mean worse outcomes for patients.
- * Experiments showed that blocking Gal3 can slow down the growth of USC cells and might help treat patients better.
Article Synopsis
- * A humanized, high-affinity antibody targeting the MUC16 ectodomain shows promise as a therapeutic agent and can be utilized in various forms, including monoclonal antibodies and chimeric antigen receptors.
- * This research provides detailed structural insights into the interaction between the antibody and MUC16, which could lead to the development of more effective cancer treatments compared to existing anti-CA125 antibodies.