Publications by authors named "D L Segev"

Central body fat distribution affects kidney function. Abdominal fat measurements using computed tomography (CT) may prove superior in assessing body composition-related kidney risk in living kidney donors. This retrospective cohort study including 550 kidney donors aimed to determine the association between CT-measured abdominal fat areas and kidney function before and after donor nephrectomy.

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Human leukocyte antigen-level matching in US kidney allocation has been deemphasized due to its role in elevating racial disparities. Molecular matching based on eplets might improve risk stratification compared to antigen matching, but the magnitude of racial disparities in molecular matching is not known. To assign eplets unambiguously, we utilized a cohort of 5193 individuals with high-resolution allele-level human leukocyte antigen genotypes from the National Kidney Registry.

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Article Synopsis
  • There's a growing population of older adults with kidney disease, but there's not enough evidence to help improve their clinical care, prompting the KDARC to conduct a study on research priorities in geriatric nephrology.
  • The study used a modified Delphi approach involving clinicians and researchers in the US and Canada to gather and prioritize important research topics for better care of older adults with kidney issues.
  • Five key research priorities were identified: improving communication about treatment options, enhancing quality of life and symptom management, addressing frailty, tailoring therapies for older adults, and providing caregiver support, all underlined by the importance of health equity and patient-centered care.
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Background: Pretransplant functional, motor, cognitive, and academic deficits are common in pediatric patients requiring heart transplantation (HT); some persist post-HT. We assessed the association between these quality of life (QoL) deficits and post-HT outcomes.

Methods: Using SRTR data 2008-2023, we evaluated the functional, motor, cognitive, and academic status of pediatric HT recipients from listing to 15 years post-HT.

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