Publications by authors named "D L Pruitt"

Article Synopsis
  • Small interfering RNAs (siRNAs) have the potential to target and silence difficult disease-related genes, providing new ways to treat diseases.* -
  • While delivering siRNAs to the liver via N-acetylgalactosamine (GalNAc) has proven effective, delivering siRNAs to other cell types remains a challenge.* -
  • Research shows that certain cellular mechanisms, including retrograde transport and lipid droplets, can enhance the effectiveness of siRNA delivery and gene silencing in both liver and non-liver cell types.*
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Physical Medicine and Rehabilitation (PM&R) residents must complete twelve months of fundamental skills training prior to beginning PM&R residency. The objective of this study is to determine if characteristics of the first post-graduate year (PGY-1) impact performance on American Board of PM&R (ABPMR) initial certification examinations. A retrospective review was conducted on a deidentified ABPMR database of physicians who completed PM&R residency and took the Part I Examination between 2008 and 2022.

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Learning new skills requires neuroplasticity. Vagus nerve stimulation (VNS) during sensory and motor events can increase neuroplasticity in networks related to these events and might therefore serve to facilitate learning on sensory and motor tasks. We tested if VNS could broadly improve learning on a wide variety of tasks across different skill domains in healthy, female adult rats.

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