Publications by authors named "D L Lefebvre"
Orbital and Ocular Venous Congestion: A Rare Manifestation of Hypervascular Paget Disease of the Bone.
Ophthalmic Plast Reconstr Surg
January 2025
A 73-year-old male with a history of incidentally diagnosed Paget disease of bone affecting the skull and left orbit 2 years prior presented with 3 months of vision loss, proptosis, and periorbital swelling of the OS. Examination showed best-corrected Snellen visual acuity of 20/150 in the affected eye, intact motility, 7 mm of relative proptosis, significant dilated and tortuous "corkscrew" conjunctival vessels, serous choroidal and retinal detachments, optic nerve hyperemia, and venous tortuosity and dilation. Although the bony lesions in the left orbit were stable from 1 year prior on imaging, the diagnostic angiogram demonstrated osseous blush and hypervascularity of the lesion.
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- The origins of snakes may trace back to either burrowing, terrestrial, or marine reptiles, with swimming ability potentially varying among different snake lineages; some may not be able to swim at all.
- A systematic review of 3,951 snake species found that 89% had no information available; however, among 454 species studied, the majority were aquatic, indicating a predominance of swimming snakes.
- Testing on 103 snake species confirmed that all could swim, suggesting swimming is common across snakes and many land vertebrates, highlighting the need for further research on the performance and ecological roles of swimming in snakes.
Article Synopsis
- - The CHILD Cohort Study is a long-term Canadian research project tracking the health and development of infants from pregnancy until adulthood, focusing on how early life environments affect disease outcomes like asthma and developmental issues.
- - The study involves detailed measurements and data collection including biological samples, environmental assessments, and psychosocial factors, with a strong participant retention rate over the years.
- - A sub-cohort was created during the COVID-19 pandemic to examine its impact on families, and the next major assessment phase will occur from 2022 to 2025, contributing valuable insights into chronic diseases and health complexities.
Article Synopsis
- Congenital enophthalmos is a rare eye condition where the eyeball is displaced backward, often linked to orbital bone issues or defects in eye development; this report details two unrelated cases caused by unusual accessory orbital muscle bands.
- The study reviewed case records of two patients with this condition, using high-resolution MRI to explore imaging features and surgical outcomes, including a 3D model for one case's surgical approach.
- Findings showed both patients had severe unilateral enophthalmos, but one required no surgery due to risks near the optic nerve, while the other didn't improve post-surgery due to scarring, highlighting the diagnostic and treatment challenges of this rare condition.
Article Synopsis
- This study evaluated how an accelerated diagnostic protocol (ADP) for cardiac chest pain affects the length of stay (LOS) in a Canadian emergency department over two years.
- It involved adults with chest pain and noted a decrease in testing intervals for non-high-risk patients, aiming to streamline processes.
- Results showed a significant LOS reduction for discharged patients (-33 minutes) while overall changes in LOS, consultations, and adverse cardiac events were not statistically significant.