Background: Millions of people suffer from traumatic brain injury (TBI) annually and many subsequently develop AD-like characteristics, but the processes occurring in the brain and the reasons for the acquisition of AD-like dementia are unknown. TBI is the leading cause of mortality in young adults and causes a huge socioeconomic burden. Improving outcomes in these patients would be a significant public health benefit.
View Article and Find Full Text PDFThe pursuit of materials, particularly plastics, with a minimal ecological footprint throughout their circular lifecycle, is crucial for advancing sustainable materials development. Living materials composed of embedded yet active organisms can leverage endogenous biotic resources to achieve functional materials that align with sustainability goals. However, current living material systems face challenges such as weak mechanical properties, limited environmental adaptability, and restricted cellular functionality.
View Article and Find Full Text PDFMurphy and Hall (2024) present two criticisms of our review of construct validity evidence reporting practices for the Reading the Mind in the Eyes Test (RMET; Higgins, Kaplan, Deschrijver, & Ross, 2024). Namely, they argue that we conflated poor reporting practices with poor validity and that our conclusions about the validity of RMET scores relied too heavily on structural validity evidence at the cost of external validity evidence. Moreover, they argue that the existing external and structural validity evidence indicates that RMET scores are generally valid for assessing emotion recognition ability.
View Article and Find Full Text PDFBackground And Aims: Novel steatotic liver disease (SLD) definitions were introduced in 2023. Accurate and meaningful classifications using clinical data are needed to study interventions and outcomes.
Methods: In a national cohort of Veterans with cirrhosis and imaging-confirmed steatosis, seven algorithms differentially emphasizing cardiometabolic risk factors (CMRFs) and alcohol exposure were developed to define alcohol-associated liver disease (ALD), metabolic dysfunction associated SLD (MASLD), and MASLD with increased alcohol intake (MetALD).