Publications by authors named "D L Gutierrez"
Nucleoredoxin (Nxn) encodes a multi-functional enzyme with oxidoreductase activity that regulates many different signaling pathways and cellular processes in a redox-dependent manner. Rare NXN mutations are reported in individuals with recessive Robinow syndrome, which involves mesomelic skeletal dysplasia, short stature, craniofacial dysmorphisms, and incompletely penetrant heart and palate defects. Here we report that Nxn is expressed in the ventral diencephalon and developing pituitary gland, and that Nxn deficient mice have pituitary dysmorphology and craniofacial abnormalities that include defects in the skull base and cleft palate.
View Article and Find Full Text PDFNucleoredoxin () encodes a multi-functional enzyme with oxidoreductase activity that regulates many different signaling pathways and cellular processes in a redox-dependent manner. Rare mutations are reported in individuals with recessive Robinow syndrome, which involves mesomelic skeletal dysplasia, short stature, craniofacial dysmorphisms, and incompletely penetrant heart and palate defects. Here we report that is expressed in the ventral diencephalon and developing pituitary gland, and that deficient mice have pituitary dysmorphology and craniofacial abnormalities that include defects in the skull base and cleft palate.
View Article and Find Full Text PDFSame-day human papilloma virus vaccination improves vaccine uptake in a dermatology sexually transmitted infection clinic: A quality improvement-based model for improving vaccination rates.
J Am Acad Dermatol
February 2025
Background: Human papilloma virus (HPV) is a prevalent sexually transmitted infection (STI) associated with malignancies and condyloma acuminata, with significant health care costs. Despite vaccine availability, vaccination rates remain low, highlighting the need for effective interventions to increase uptake.
Objective: To improve HPV vaccination rates among eligible individuals at a safety-net dermatology STI clinic.