Publications by authors named "D L GERARD"

In tetraploid F1 populations, traditional segregation distortion tests often inaccurately flag SNPs due to ignoring polyploid meiosis processes and genotype uncertainty. We develop tests that account for these factors. Genotype data from tetraploid F1 populations are often collected in breeding programs for mapping and genomic selection purposes.

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End-to-end linked nanorod dimer nanogap antennas exhibit superior plasmonic enhancement compared to monomers due to the coupling of localized surface plasmon resonances (LSPR) of individual nanorods. However, controlling the assembly to stop at the dimer stage is challenging. Here, we report a pH-controlled synthesis of Au nanorod dimer nanogap antennas in an aqueous solution using 1,4-dithiothreitol (DTT) as a linker.

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Background: Point-of-care electroencephalography (EEG) devices can be rapidly applied and do not require specialized technologists, creating new opportunities to use EEG during prehospital care. We evaluated the feasibility of point-of-care EEG during ambulance transport for 911 calls.

Methods: This mixed-methods study was conducted between May 28, 2022 and October 28, 2023.

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Article Synopsis
  • - The study used constraint-based network modeling to analyze metabolic networks at a genomic scale, integrating RNA-seq data with epigenomic data from the EpiATLAS resource across 1,555 samples from 58 tissues and cell types.
  • - The analysis identified both core metabolic processes essential for all cells and unique metabolic functions specific to certain cell types, helping to define the metabolic identity of different human cells and tissues.
  • - By examining enhancer-gene interactions and gene-level chromatin states, the research revealed critical nodes and regulatory points that control metabolism, highlighting how certain pathways are repressed in inactive cell types.
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