[Search for new modes of antibiotic prophylaxis of septic complications after percutaneous nephrolithotripsy].

The risk of infectious and inflammatory complications after PNL is based on presence of microorganisms in the form of biofilms inside the stone. Destruction of stones during surgery or lithotripsy may be a trigger for the growth of microorganisms that are integrated into the biofilms, and the migration of bacteria and their toxins in the blood flow under pressure of irrigation fluid can cause septic complications. The danger of infectious and inflammatory complications after percutaneous interventions for kidney stones requires a search for specific antibiotics for antimicrobial prophylaxis and efficient modes of their administration.

Placebo-controlled dose-ranging phase 2 study of subcutaneously administered LHRH antagonist cetrorelix in patients with symptomatic benign prostatic hyperplasia.

Background: Pilot studies with daily dosing suggested the use of the luteinizing hormone-releasing hormone antagonist cetrorelix (CET) for the treatment of symptoms from benign prostatic hyperplasia (BPH).

Objective: To assess efficacy and safety of three dosing schemes of CET in patients with symptomatic BPH.

Design, Setting And Participants: After a run-in period with 4 weekly injections of placebo, 140 patients with an international prostate symptoms score (IPSS) > or =13 and a peak urinary flow rate (PFR) 5-13ml/s were randomly allocated to 4 treatment groups; patients with residual urine volume of >350ml were excluded.

[Prevalence of essential urological diseases among rural population of Uzbekistan].

A retrospective one-stage epidemiological trial was made to investigate prevalence of urinary infections (UI), urolithiasis (UL) and benign prostatic hyperplasia (BPH) among rural population, to reveal latent or initial stages of these diseases and to specify preventive policy. 2330 rural one-year-olds and older children (n = 345, 14.8%) were covered by a screening examination for bacteriuria, leukocyturia, crystaluria and symptoms of the lower urinary tract caused by benign prostatic hyperplasia (BPH).

[Modification of the test pressure-flow for evaluation of detrusor contractility in absence of urination].

The aim of the study was design and validation of the test for examination of detrusor contractility in the absence of urination. The method consists in registration of detrusor pressure in maximal speed of urinary flow in the course of artificial urination using Foley's catheter. Urethral resistance was modeled by raising drainage up to 40 cm above the level of the symphysis which was adjusted and found optimal in 48 of 179 examinees.

[A new method of radiofrequency needle ablation of the prostate in the treatment of benign hyperplasia].

The authors present the results of a new transvesical approach for radiofrequency needle ablation of the prostate in 29 patients with benign prostatic hyperplasia (BPH). The ablation has been done using a new radiofrequency generator ESHFG-440-40-1 made in Russia. Upon 12-month follow-up urination normalized in 23 patients.