Non-RB1 germline cancer predisposing variants found in retinoblastoma patients.

Purpose: It is well known that individuals with hereditary retinoblastoma are at lifelong high risk for developing subsequent malignant neoplasms (SMN). However, the role that non- germline variants play in tumorigenesis and SMN risk has not yet been studied. The purpose of this study is to report the frequency and spectrum of non- germline cancer predisposing variants in individuals with retinoblastoma (RB).

The influence of risk perception on disaster recovery: A case study of new Jersey families impacted by hurricane sandy.

Introduction: Risk perceptions of extreme weather events have been explored extensively through the lens of emergency preparation, but the influence of pre-storm risk perceptions on resilience and recovery trajectories are understudied. The objective of this qualitative analysis is to explore 1) the factors which shape residents' perception of risk prior to an event, and 2) how these factors contribute to 'sensemaking,' after the storm to influence experiences of recovery.

Methods: Eight focus groups and ten in-depth interviews (N = 38) from the Hurricane Sandy Child Impact Study were analyzed using grounded theory.

Ethnic and Racial Disparities in Self-Reported Personal Protective Equipment Shortages Among New York Healthcare Workers During the COVID-19 Pandemic.

Introduction: To assess the association of race and ethnicity with self-reported personal protective equipment shortages during the COVID-19 pandemic among healthcare workers in New York.

Methods: The COVID-19 Healthcare Personnel Study of New York was a prospective cohort study of HCWs with baseline data collected in April 2020 and follow-up data collected in February 2021. Multivariable logistic regression modeling was used to estimate the adjusted OR and 95% CIs of personal protective equipment shortages associated with race and ethnic minority status.

Subfoveal Choroidal Thickness in Patients with Histiocytosis and Multimodal Imaging Features of Choroidal Infiltrates.

Purpose: To evaluate choroidal findings in patients with histiocytosis, including subfoveal choroidal thickness (SFCT), and multimodal imaging in eyes with choroidal infiltrates visible by ophthalmoscopy and determine if abnormalities change with histiocytosis-directed (kinase inhibitor) therapy.

Design: Retrospective comparative study at single tertiary cancer referral center.

Participants: Ninety-one patients with histiocytosis and 41 age- and sex-matched controls.

Vitreoretinal lymphoma: the importance of cerebral spinal fluid evaluation at initial diagnosis.

Background/aims: To determine if patients with vitreoretinal lymphoma (VRL) and concomitant central nervous system lymphoma (CNSL) may present without brain MRI findings, but possess cerebrospinal fluid (CSF) suspicious for lymphoma.

Methods: This was a retrospective, single-centre, observational study evaluating patients with a diagnosis or suspicion of VRL seen at Memorial Sloan Kettering Cancer Center between 2006 and 2024. Patients were included if the final diagnosis was biopsy-proven CNSL and both MRI brain with and without contrast±CSF evaluation (obligatory for inclusion if MRI negative) were performed at the initial diagnostic workup.