A six-year longitudinal study of neurocognitive problems in children with epilepsy.

Introduction: This study describes the specific neuropsychological abnormalities among children with epilepsy (CH-E) living in Georgia.

Methods: A cohort of CH-E and children without epilepsy (CH-NoE), aged 6-13 years, admitted to the epilepsy center of the Institute of Neurology and Neuropsychology from 1st January 2010 to 31st December 2015, was selected and investigated with a structured protocol. Neurological/epileptological assessments were made and neuropsychological testing was done on all study subjects.

Focal EEG features and therapeutic response in patients with juvenile absence and myoclonic epilepsy.

Objective: To investigate the characteristics of focal EEG features in patients with juvenile absence epilepsy (JAE) and juvenile myoclonic epilepsy (JME), and to assess their possible influence on therapeutic response.

Methods: Focal EEG features were prospectively scored in 168 consecutive patients. Ninety-six patients were drug-naïve and 72 patients were already on antiepileptic drugs (AEDs): 38 on adequate medication and 34 on inadequate medication.

The prevalence and treatment gap of epilepsy in Tbilisi, Georgia.

Introduction: Data on the prevalence of epilepsy and the extent of its treatment gap are important for planning health care delivery for people with epilepsy. The prevalence of active epilepsy in Georgia prior to the social and political re-organization in the early 1990s was estimated at around 5.7 per 1000.

Auditory brainstem response, middle-latency response, and slow cortical potential in patients with partial epilepsy.

Auditory brainstem responses (ABRs), middle-latency responses (MLRs), and slow cortical potentials (SCPs) have been recorded in patients with partial epilepsy previously untreated by anticonvulsants. Peak latencies, interpeak intervals, and amplitudes were estimated and the mean group values were compared with the respective data in age- and gender-matched healthy individuals. Neither ABRs nor MLRs in the patients differed significantly from those in the control group.

Effects of carbamazepine on auditory brainstem response, middle-latency response, and slow cortical potential in epileptic patients.

Auditory brainstem responses, middle-latency responses, and slow cortical potentials (ABRs, MLRs, SCPs) were recorded in 21 epileptic patients before and during treatment with carbamazepine (CBZ). The peak-latencies, interpeak intervals, and amplitudes were estimated and evaluated statistically. CBZ monotherapy resulted in prolongation of peak latencies of ABR waves I, III, and V as well as of interpeak intervals I-III and I-V.