Publications by authors named "D Kulaj"
Article Synopsis
- Mastitis is a complex inflammatory condition in dairy cattle that is increasingly hard to treat due to antibiotic resistance, prompting research into alternative therapies like mesenchymal stem cells (MSCs).
- This study investigated the effectiveness of allogeneic MSCs derived from bone marrow (BMSC) and adipose tissue (ADSC) for treating mastitis in 39 Polish Holstein-Friesian cows, with various administration methods evaluated.
- Results showed that the use of MSCs led to a significant reduction in bacterial counts and somatic cell count in milk, especially with combined intravenous and intramammary treatments.
The aim of this study was to identify the c.495C > T polymorphism within exon 1 of the osteopontin gene (OPN), and to analyze its association with susceptibility to ketosis in Polish Holstein-Friesian (HF) cows. The study utilized blood samples from 977 HF cows, for the determination of β-hydroxybutyric acid (BHB) and for DNA isolation.
View Article and Find Full Text PDFIn the recent years, antioxidant properties of food products have become an important aspect for consumers. Milk is a very good source of easily absorbable proteins and minerals, as well as a valuable source of antioxidants. Lipocalin-2 (LCN2), given that, inter alia, it is produced in large quantities by various types of cells in response to oxidative stress caused by physical or chemical factors, it can be considered a protein that determines the total antioxidant capacity of milk.
View Article and Find Full Text PDFThe major histocompatibility complex in cattle (BoLA) is regulated by genes that are closely related to the development of the immunological response to pathogens. The most polymorphic BoLA-DRB3.2 locus was analysed in 209 black-and-white Holstein-Friesian cows in Poland in order to a better explanation of influence of MHC on immunity to diseases in dairy cattle.
View Article and Find Full Text PDFMyeloperoxidase (MPO) is an important enzyme, which is one of the components of the antibacterial system in neutrophils and monocytes. MPO participates in the inflammatory response in multiple locations in the body, including the mammary glands. As a result of the activity of MPO, many oxidising compounds as well as reactive oxygen species are generated.
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