A critical review of hypopharyngeal carcinomas--1975-1985.

Seventy-seven patients with hypopharyngeal carcinomas who presented to Groote Schuur Hospital between 1975 and 1985 are reviewed. Of these patients 76.6%, mostly with pyriform fossa tumours, had advanced disease.

Major surgery of oral and oropharyngeal carcinoma.

Thirty-two composite resections were carried out in the Department of Otolaryngology at Groote Schuur Hospital for oral and oro-pharyngeal squamous carcinoma over the 10-year period, 1977-1986. Three patients were lost to review but all others were followed up to death or to five years. Twenty-seven patients underwent surgery as their primary procedure and five for recurrence after primary radiotherapy.

Case report 720. Multicentric mixed tumor of bone with pulmonary involvement.

A man presented with a mass in the left first metacarpal bone. Later, his chest radiograph showed extensive, bilateral, rounded opacities in both lungs with enlarged hilar lymph nodes, and he developed expanding lesions in the left radius, ulna, and metacarpal bones. The pulmonary lesions were treated with radiotherapy and cytotoxic agents, and the tumor mass in the first metacarpal was debulked.

Malignant transformation in fibrous dysplasia. A report of 3 cases.

Three patients with fibrous dysplasia were encountered in whom osteosarcoma subsequently developed. A review of published reports and the authors' experience establishes fibrous dysplasia as a premalignant bone lesion. Radiation appears to enhance the inherent tendency towards malignant transformation.

Synovial sarcoma of the hand--a literature study.

Ninety cases of synovial sarcoma of the hand, including eight case reports have been described during the last fifty years, (1934-1984). 8.5% of all synovial sarcomata involve the hand, and affect predominantly individuals under the age of thirty.